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Erich C. Blossey, Ph.D. D. M. and J. M. Cram Chair of Chemistry |
Office: (407) 646-2140 |
I received a B. S. degree in chemistry from Ohio State University in 1957 (mentor: Michael Cava), a M. S. of degree in organic chemistry from Iowa State University (1959, mentor: Ernest Wenkert), and a Ph.D. degree in 1963 under the direction of Mordecai Rubin from Carnegie Institute of Technology (Carnegie-Mellon University). Postdoctoral fellowship from NIH was taken at Stanford University with Professor Carl Djerassi (1962-1963), and an industrial postdoctoral fellowship at Syntex, S. A. in Mexico City, Mexico (1963-1964). After obtaining a Kettering-Great Lakes Colleges Internship at Wabash College (1964-1965), I joined the faculty of Rollins College in the fall of 1965. After attaining the rank of professor (1975), sabbatical research studies took place at University of New Mexico (with Professor Douglas Neckers, 1974-1975), Oklahoma State University (1984-1985, with Professor Warren Ford), and Harvard University (1991-1992, with Mallecrodt Professor of Chemistry, George Whitesides).
Teaching Interests:
My teaching is largely in the area of bioorganic chemistry with special interests in application of mechanistic organic chemistry and spectroscopic techniques. Considerable attention has been directed to the use of active learning methods such as Personalized System of Instruction, web-based learning tools (Blackboard) and the Pers August 12, 2005 e following courses:
Organic Chemistry I and II (CHM 220, CHM 221)
Instrumental Analysis (CHM 380)
Biochemistry (BCH 431)
Chemical Investigations II and III (CHM 389 & CHM 488)
General Chemistry I and II (CHM 120, CHM 121)
Physics-Chemistry (PC 120/121)
Photography: The Science and Art (CHM 111)Research Interests:
An effort, some thirty years ago was directed to find investigations that would be appropriate for undergraduate students. As a result, I began a series of investigations into polymer-supported reagents and reactions. This type of research provided the students with easy work-up of reactions. We have been successful in exploring a number of projects involving polymer-supported oxidants in synthetic procedures, thiol/disulfides for protein folding studies, steroids for study of selective matrix effects and bioorganic mimics of coenzymes. Recent studies have been in a collaborative effort with Prof. M. P. Doyle (University of Maryland) on binding rhodium (II) chiral ligands as catalysts for use in carbene reactions. A second collaboration has focused on new approaches to polymer-thiol and disulfide reagents with Prof. Watson J. Lees (Florida International U.).
Significant Publications:
“Preparation and Catalytic Properties of Immobilized Chiral Dirhodium (II) Carboxamidates” Michael P. Doyle, Daren J. Timmons, Jennifer S. Tumonis, Han-Mou Gau, and Erich C. Blossey, Organometallics, 2002, 21,1747-1749.
“Catalysts with Mixed Ligands on Immobilized Supports. Electronic and Steric Advantages” Michael P. Doyle, Ming Yan, Han-Mou Gau, and Erich C. Blossey, Organic Letters, 2003, 5, 561-563.
“Use of Affinity Capillary Electrophoresis to Determine Kinetic and Equilibrium Constants for Binding of Arylsulfonamides To Bovine Carbonic Anhydrase” Luis Z. Avila, Yen-Ho Chu, Erich C. Blossey and George M. Whitesides, Journal of Medicinal Chemistry , 1993, 36, 126-133.
"Synthesis, Reactions and 13C FT-NMR Spectroscopy of Polymer Bound Steroids," Erich C. Blossey, Randal G. Cannon, Warren T. Ford, M. Periyasamy and S. Mohanraj, Journal of Organic Chemistry, 1990, 55, 4664-4668.
"Polymer-Based Sensitizers for Photoöxidations. II." A. Paul Schaap, Arthur L. Thayer, Erich C. Blossey, and Douglas C. Neckers, Journal of American Chemical Society, 1975, 97, 3741.
